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What Dosage of CBD Should You Take?

Steven Gans, MD is board-certified in psychiatry and is an active supervisor, teacher, and mentor at Massachusetts General Hospital.

Iryna Veklich / Getty Images

CBD is available in a number of different formulations including creams, tablets, oils, and gummies. These can vary in terms of their ingredients as well as dosages, and there is not a great deal of research available on what dose might be beneficial or safe to treat certain conditions.

Cannabidiol (CBD) is the second most abundant cannabinoid found in marijuana. Unlike tetrahydrocannabinol (THC), CBD does not have psychoactive effects. Interest in the use of CBD for health purposes has grown tremendously in the last few years.

CBD is believed to have a range of positive physical and mental health effects. Because of this, it has become increasingly popular as a way to alleviate everything from anxiety to sleep disorders.

In order to determine if CBD is right for you, it is important to consider its potential benefits, side effects, and available research on safe dosages.

Possible Benefits

CBD is just one of hundreds of different compounds found in the cannabis plant. While cannabis has been used in holistic medicine for many years, only recently have researchers begun to explore some of the medicinal purposes for CBD and other cannabinoids.

While further research is still needed, there is some evidence that CBD may have some beneficial mental health effects. These include:

  • Alleviating depression: Some research also indicates that CBD may be useful as a treatment for depression. Studies suggest that the cannabinoid might have an influence on how the brain responds to serotonin, a neurotransmitter that plays a key role in mood.   People with depression sometimes have a low level of serotonin, so CBD may help the brain use available serotonin more effectively.
  • Improving sleep: While the reasons are not entirely understood and require further research, CBD also appears to have potential as a treatment for sleep problems. For example, one study found that people who took CBD also reported improvements in the quality of their sleep.  
  • Reducing anxiety: Anxiety is one of the most common types of mental health conditions, affecting almost 20% of American adults each year. Research suggests that CBD may help alleviate acute symptoms of a number of anxiety-related conditions including generalized anxiety disorder, obsessive-compulsive disorder, and social anxiety disorder.  

In addition to the mental health benefits, CBD may also have therapeutic benefits for a range of other conditions. The World Health Organization suggests that CBD may have beneficial effects in the treatment of:  

  • Alzheimer’s disease
  • Arthritis
  • Cardiovascular disease
  • Diabetes
  • Infection
  • Inflammation
  • Multiple sclerosis
  • Nausea
  • Pain
  • Psychosis

It is important to remember that these benefits have not yet been conclusively proven. More research is needed to determine the role that CBD might play in the treatment of different disorders and health conditions.

Research

There have been a number of studies that suggest that CBD may have a number of different physical and mental health uses. However, more research is still needed to better understand the substance’s potential applications and possible long-term side effects.

A 2019 comprehensive review published in The Lancet Psychiatry looked at previously published studies.   The review ultimately concluded that there was little evidence to support the use of CBD for mental health purposes and suggested that more research is needed in order to substantiate its use to treat symptoms of conditions such as anxiety, depression, and insomnia.

It is important to remember that this doesn’t mean that CBD isn’t effective. Many of the studies that were included in the review were small, had few participants, and were not randomized controlled trials.

This suggests that more research involving more participants and well-designed studies is needed in order to better understand if, how, and why CBD works.

While its effectiveness is still up for debate, one 2017 review found that it was a relatively safe option.   While it is important to remember that there is still a great deal we don’t yet know about CBD and its effects, it is something that you might opt to try to see if you experience any benefits.

How Much Should You Take?

The dosages used in research studies vary and there is no consensus on how much should be used for specific conditions. If you do decide to try CBD, it is also important to note that there is no universally agreed upon dose. Research also suggests that people may respond differently to various dosages, so the amount that is right for your needs might vary.

CBD Dosages

Some dosages that have been used in research studies for different conditions include:

  • Anxiety: 300 to 600 mg  
  • Bowel disease: 10 mg per day  
  • Cancer-related pain: 50 to 600 mg per day  
  • Parkinson’s disease: 75 to 300 mg per day  
  • Poor sleep: 25 mg per day  
  • Psychosis: 600 mg per day  

One 2020 review of studies found that participants showed improvements in anxiety levels after single doses of CBD ranging from 300 to 600 mg.   Such results indicate that the CBD may hold promise as a treatment to alleviate symptoms of acute anxiety.

It is important to remember that you should always talk to your doctor before using CBD if you have symptoms of a serious mental or physical health condition. CBD could potentially worsen symptoms or interact with other medications you are taking.

Looking at the dosage information for the CBD product that has been FDA approved can also be helpful. For Epidiolex, an FDA-approved cannabis-derived medication used to treat seizures in people with certain types of epilepsy, the starting dosage is 5 milligrams per kilogram of body weight. This dose can later be increased to 5 mg per kilogram of body weight twice a day.

Other CBD products are not FDA regulated and do not have officially recommended dosages. This can make it difficult to determine how much you might need, but there are some things you can consider that might help.

  • Assess your sensitivity to CBD: Your individual ability to tolerate CBD can also play a role in determining how much you need. If you are very sensitive to the effects of CBD, you should take a small dose. Some people may find that they are not as affected by the substance, so they may need to take a larger dose to notice any beneficial effects.
  • Consider individual factors: When you are trying to decide how much CBD to take, there are a number of factors you should consider. These include the formulation and concentration of the capsule, oil drops, or gummies you are taking, the symptoms you are treating, and your age, sex, weight, and overall health. Generally, people with heavier bodies need to take a little more to achieve the same effects. Men may need a larger dose, while older people may need less.
  • Consider the symptoms you’re treating: The symptoms you are trying to alleviate can also play a role in the CBD dosage you need to take to see results. In one study, participants who took 25mg of CBD each day had improved sleep quality, although the results were not consistent.   However, you might find that you need a lower or higher dose if you are treating another type of condition.
  • Try a dosage calculator: Researchers note that while the variety of dosing strategies and formulations make it difficult to determine efficacy, there are a number of online “dose-calculators” available online (such as mydosage.com) that are designed to help people choose the correct dose.   The accuracy of such calculators is difficult to assess, but it may be a good place to start.

Before you try CBD, discuss your plan with your doctor. They may be able to recommend a dose and help you better understand any potential risks, complications, side effects, or interactions you might experience.

Start With a Low Dose

Unless your doctor recommends a specific dose, start by taking 10 to 20 mg a day. Take this for a week to ensure that it is well-tolerated and that you don’t experience any unwanted effects or an allergic reaction.

If this dose does not have the desired effect, try increasing in increments of 5mg each week until the desired amount is reached.

In studies, amounts vary from as low as 20 milligrams per day to up to 1,500 milligrams (mg) per day. The World Health Organization reports that dosages in clinical research studies typically range between 100 and 800 milligrams per day.  

Is It Possible to Take Too Much?

So what is the maximum amount of CBD you should take? Researchers have found that 600 mg per day appears to be safe, but one study suggested that doses of up to 1,500 mg a day are safe and tolerated well.  

However, it’s important to remember that research is still in its infancy and experts do not yet fully understand the potential long-term impacts of CBD usage. For that reason, you should always discuss your CBD use with your doctor.

Starting at a lower dose and working your way up to the amount you need may be the best ways to avoid taking too much.

How to Take CBD

The amount of CBD found in a product may depend on different factors, including the formulation and method of administration. CBD products are available in a number of different forms including oils, capsules, tablets, nasal sprays, and gummies.

One of the most popular ways to take CBD is as an oil. Such products are made by combining CBD with some type of carrier oil, such as coconut oil. Some more recently developed products include dietary supplements, foods, beverages, lotions, salves, and cosmetics.

The type of CBD product you choose may depend on what you are trying to treat. If you are looking for general mood improvements, a dietary supplement might be a good option.

If you are targeting specific symptoms of a condition, taking an oil, capsule, or gummy might be a better way to obtain a higher, more concentrated dose.

Topical applications may produce localized effects, but they are unlike to have any mental health benefits.

What Kind Should You Take?

It’s also important to remember that many products don’t contain just CBD on its own. There are three types of CBD available:

  • Isolate contains CBD and only CBD.
  • Broad-spectrum contains CBD and other cannabinoids, but not THC.
  • Full-spectrum contains CBD, THC, and other cannabinoids.

It may be helpful to take a broad-spectrum product since research suggests that CBD’s effects may be most beneficial when taken in conjunction with other cannabinoids, a phenomenon known as the entourage effect. CBD may also help mitigate some of the effects of THC.

Side Effects

While CBD is generally well-tolerated, this does not mean that you won’t experience any side effects.

Some of the most common side effects that people experience when taking CBD include:

  • Appetite changes
  • Diarrhea
  • Nausea
  • Dizziness
  • Stomach upset
  • Weight changes

Some recent research has generated concerns over the safety and potential long term effects of CBD. One study involved giving mice an equivalent of the maximum dose of the CBD medication Epidiolex, which is used to treat certain forms of epilepsy. The results indicated an increased risk for liver damage as well as concerns over its interaction with other medications.  

Safety

It is also important to remember that CBD products are not regulated by the U.S. Food and Drug Administration (FDA). Some manufacturers make unproven claims about the uses and efficacy of their products. There is also concern about the quality and safety of the products themselves.

One report by the Centers for Disease Control and Prevention (CDC) indicated that a number of people experienced negative unwanted side effects due to CBD products that contained synthetic CBD, although the products were not labeled as containing such ingredients.  

Mislabeling appears to be a fairly common problem with CBD products. In one study, 70% of the CBD products that were sold online contained significantly more of the psychoactive ingredient THC than the label indicated.  

Federal law prohibits the sale of products that contain more than 0.3% THC. States laws also vary, so you should always check with your state before buying CBD products online.

A Word From Verywell

If you do decide to take CBD to alleviate an acute or chronic condition, remember that the amount that you take will depend on a variety of factors. Finding the right dosage often takes some experimentation and adjustments. Starting with a low dose and then gradually increasing the amount you take until you achieve the desired effects is the best approach.

CBD holds promise as a treatment for a range of conditions, but how much should you take? Learn more about CBD dosages for different purposes.

CBD Dosage: Figuring Out How Much to Take

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You’ve probably heard about the health benefits of CBD, but how much should you take to feel those?

Cannabidiol, or CBD, is one of over 60 active compounds in the cannabis plant. These active compounds, known as cannabinoids, affect your body in many different ways.

CBD isn’t psychoactive — meaning it won’t get you “high.” Instead, research suggests that it may help:

  • reduce anxiety and depression
  • improve sleep
  • reduce seizures in people with epilepsy
  • soothe pain and inflammation
  • improve heart health
  • improve symptoms of inflammatory bowel disease (IBD)

No matter what condition you’re trying to treat with CBD, giving yourself an adequate dosage is key — or it might not work for you.

It can be tough to figure out how much CBD you should take, as CBD isn’t currently regulated by the Food and Drug Administration (FDA), and there are no official recommended dosages.

Here’s what you need to know about figuring out how much CBD to take.

CBD has been the subject of a lot of discussion and research over the past few years.

As this 2017 review shows, a great deal of research has found that it’s a relatively safe treatment. The studies analyzed in that review didn’t show that there’s one universal dosage of CBD that everyone should take. Instead, it underscored the fact that different people (and, in the animal studies, different animals) respond to different dosages of CBD. Most of the human studies use dosages anywhere between 20 and 1,500 milligrams (mg) per day.

It’s worth remembering that there’s still a lot about CBD that we don’t know. As the cannabis industry grows, researchers will likely conduct more studies on cannabis, including marijuana and hemp, and its derivatives.

The amount of CBD you should take depends on a range of factors, including:

  • your body weight
  • the condition you’re treating
  • your individual body chemistry
  • the concentration of CBD in each pill, capsule, drop, or gummy

In other words, there are a lot of variables that go into deciding how much CBD to take. Before trying CBD, be sure to talk to your doctor about an appropriate dosage and any potential risks. If your doctor tells you how much to use, stick to their recommendation. This is especially important if you’re taking a prescription medication that contains CBD, such as Epidiolex, a form of seizure medication.

If your doctor doesn’t provide a recommendation, it’s best to start with a smaller dosage and gradually increase it. This could mean starting with 20 to 40 mg a day. After a week, increase this amount by 5 mg. Continue this until you feel that it’s effectively treating your symptoms.

For example, you might start off with 40 mg to treat severe pain. You can take 40 mg on days when you’re in a lot of pain. After a week, you increase it to 45 mg, and after a second week, you use 50 mg. At this point, you might feel that your pain is bearable.

It might be wise to keep track of how much CBD you’re taking and whether your symptoms are getting better. Write it down on paper or in a notes app on your phone.

Summary

Start with a small dosage of CBD and increase slowly until you reach your desired effect. Your ideal dosage of CBD depends on a lot of factors, like your body weight, body chemistry, the condition you’re treating, and the concentration of CBD in the product you’re using.

How to calculate dosage

Some products, such as CBD gummies, capsules, or pills, tell you how much is in a single serving. For example, the packaging on a bottle of CBD capsules might indicate that there are 5 mg of CBD per capsule.

If you’re using CBD oil, it’ll likely come in a dropper bottle. The packaging might specify how much CBD is in a single drop. From there, you can figure out how many drops you need to use.

Sometimes it’s harder to figure out how much CBD is in one drop because the packaging specifies the total amount of CBD in the entire bottle, but not the amount that will be in a single drop.

One drop is about 0.05 milliliters (mL). That is, not a full dropper — just a single drop.

This means that a 10-mL bottle of CBD oil contains 200 drops. And if the packaging for that 10-mL bottle says that the bottle contains 1,000 mg of CBD, each drop will contain about 5 mg of CBD.

So, to have 20 mg of that type of CBD oil, you should take four drops.

CBD has many health benefits, but it can be hard to figure out how much to take. Get tips on dosage here.