CBD Oil and Heart Failure
Could CBD oil ease your heart failure symptoms or help you manage your condition? This herbal supplement is sold over the counter and may be marketed with various health claims, but heart experts aren’t so sure it’s worthwhile or even safe if you have heart failure.
“Heart failure patients should know that while CBD has been touted as a wonder compound and seems to be in almost everything these days, it has never been shown to have any significant cardiovascular benefits in human studies,” says Scott Lundgren, DO, a transplant cardiologist at Nebraska Medicine in Omaha.
What Is CBD Oil?
CBD oil contains cannabidiol, an herbal liquid supplement made from the cannabis plant. It doesn’t have the same effect on the brain as THC, another compound found in cannabis that gives you a “high” when smoked or eaten, says Larry Allen, MD, associate division head for clinical affairs in cardiology at University of Colorado Anschutz Medical Campus.
“There are no known cardiovascular benefits for cannabis or cannabidiol, and there may even be some adverse effects, so people should not take these products and think that it will have positive effects on their cardiovascular health,” says Allen, who’s also co-author of the American Heart Association’s statement on all cannabis products.
In 2018, the FDA approved the first oral, purified CBD drug, Epidiolex, to treat seizures in two rare forms of epilepsy. Two synthetic versions of cannabidiol were later approved: dronabinol (Marinol, Syndros) for treatment of nausea during cancer chemotherapy and nabilone (Cesamet) to treat weight loss associated with AIDS.
Some of CBD’s proven benefits in other health conditions may be intriguing to people living with heart failure, Allen says.
“Does it stimulate your appetite? Yes. Do people gain weight if they take it? Possibly true. Patients with severe heart failure do have cachexia,” or severe weight loss and muscle wasting, he says. “One could argue that people with nausea, lack of appetite, or who are losing weight could think CBD would help them. People with heart failure have a fair amount of discomfort, including edema [swelling] and somatic or pain-related issues, so you could think CBD has a role.”
But there isn’t really any evidence to prove that it will relieve heart failure symptoms or be safe to use if you have heart failure, he adds.
What We Know About CBD
Some research suggests that CBD oil may improve some heart-related symptoms:
- A very small study conducted in 2017 in England found that CBD improved resting blood pressure and blood pressure spikes related to stress in people without heart conditions.
- Various studies in animals have shown that CBD could improve vasorelaxation, or opening of arteries for better blood flow, as well as reduce inflammation. A small clinical trial from Mexico studying CBD in people with heart failure hasn’t reported any results yet.
- A large study of more than 161,000 people hospitalized for heart failure who had used marijuana found that they had, on average, a lower risk of death and shorter hospital stays. But this doesn’t necessarily mean CBD oil would have the same benefit.
It’s illegal in the U.S. to market CBD by adding it to any food or calling it a dietary supplement. Also, although the FDA has approved a few CBD drugs to treat certain diseases, don’t expect CBD sold over the counter to be safe or beneficial for heart failure, Lundgren says.
“CBD oil may not have the same properties, and it can actually cause gastrointestinal distress like diarrhea or cause decreased appetite. CBD products can include unknown ingredients and may not be accurately labeled,” he says.
When you use CBD oil, your liver breaks it down. During this process, it could interfere with your medications for heart failure or other heart conditions. “CBD has known interactions with warfarin, certain statins, calcium channel blockers, beta-blockers, and nitrates. Just because a supplement is ‘natural’ doesn’t mean that it is safe,” Lundgren says.
CBD May Have Health Risks
CBD oil must be studied in randomized clinical trials on people, not animals, before it can be considered safe or effective for heart failure, Lundgren says. Until that happens, he advises against buying or using CBD. “There is some evidence that CBD can cause liver injury as well as lead to male infertility issues. When consumed with alcohol, individuals may experience increased drowsiness, which can lead to household injuries.”
If you have heart failure, you might feel like you’re taking control of your own care by trying herbal treatments that don’t require a prescription. To be safe, talk to your cardiologist first: Ask questions about CBD oil and make decisions together about using this or any other supplement, Allen says.
“CBD products cost money and can distract you from taking prescribed treatments for heart failure that are evidence-based. They could do indirect harm to people with heart failure. . We already have a half-dozen treatments for heart failure symptoms and to help you live longer.”
Larry Allen, MD, MHS, University of Colorado Anschutz Medical Campus.
Scott Lundgren, DO, Nebraska Medicine.
FDA: “What You Need to Know (And What We’re Working to Find Out) About Products Containing Cannabis or Cannabis-derived Compounds, Including CBD,” “FDA Approves First Drug Comprised of an Active Ingredient Derived from Marijuana to Treat Rare, Severe Forms of Epilepsy,” “FDA and Cannabis: Research and Drug Approval Process.”
JCI Insight: “A single dose of cannabidiol reduces blood pressure in healthy volunteers in a randomized crossover study.”
Oxidative Medicine and Cellular Longevity: “Therapeutic Applications of Cannabinoids in Cardiomyopathy and Heart Failure.”
Cannabis and Cannabinoid Research: “An Update on Safety and Side Effects of Cannabidiol: A Review of Clinical Data and Relevant Animal Studies.”
ClinicalTrials.gov: “Cannabidiol in Patients With Heart Failure in AHA/ACC Stages A-C (CAPITAL-AC).” NCT03634189.
Journal of Cardiac Failure: “Marijuana Use is Associated with Better Hospital Outcome in Patients with Acute Heart Failure: A Propensity Match Analysis from National Inpatient Database.”
CBD oil is made from cannabis plants but won’t make you high. Still, this natural supplement could interact with some heart medicines. Find out what you need to know before you try CBD oil for heart failure.
CBD and Heart Arrhythmia: What We Know So Far
The relationship between CBD and arrhythmia is somewhat complicated.
Contemporary scientific research shows that CBD has a potentially beneficial effect on arrhythmia, and on the cardiovascular system as a whole.
On the other hand, a small percentage of people experience an increased heart rate and heart palpitations when they use CBD, which are known symptoms of arrhythmia.
Before we get into more details of the research, let’s briefly explain arrhythmia.
Cardiac arrhythmia is a group of conditions characterized by an irregular heartbeat, where the heart either beats too rapidly or too slowly.
One of the main symptoms of arrhythmia are heart palpitations, which are characterized by increased awareness of the contraction of the heart, often accompanied by the hard and irregular beating of the heart.
Unlike CBD, which is non-psychoactive, THC (the most abundant psychoactive cannabinoid in the cannabis plant) is known to cause rapid heartbeat and heart palpitations.
This especially happens to novice users, but also if the user consumes too much THC at once.
Smoking Too Much Cannabis? Here’s How to Overcome It
This occurs because THC significantly lowers blood pressure, which causes the heart to pick up the pace and beat faster.
For a very large percentage of users, CBD doesn’t produce this effect but some people do experience irregular heartbeats and heart palpitations from consuming cannabidiol.
A good example of how rarely this happens is this 2019 study, which analyzed the effects of CBD on people suffering from chronic pain.
This research had 97 patients (30 to 65 years old), and only one of them experienced an increased heartbeat from using CBD.
Patients were using two soft gels per day for 8 weeks, and each soft gel contained 15.7mg of CBD, and 0.5mg of THC.
The woman who experienced a rapid heartbeat reported that the treatment “made her heart race”.
The reasons behind this occurrence are still unknown, but if it happens to you, it’s important to understand the difference between CBD products.
Full-spectrum CBD products have a significant amount of THC, and other minor cannabinoids and terpenes are also present in these products.
If you’re especially sensitive to THC, these types of products can definitely induce a rapid heartbeat and palpitations.
Compared to full-spectrum products, broad-spectrum CBD products have a lesser amount of THC in them, and they also contain minor cannabinoids and terpenes.
Broad-spectrum products are far less likely to induce palpitations, although it’s still possible.
Finally, CBD isolates are the third type of CBD products. They only contain CBD, and nothing else. These products are least likely to cause a racing heart or palpitations.
Full Spectrum CBD vs CBD Isolate: Which Should You Choose?
It’s important to mention that CBD isolates are considered the least beneficial type of CBD products because cannabinoids work synergically in the body.
This synergistic cooperation of different cannabinoids is known as the entourage effect, because the presence of THC and other cannabinoids increases the health benefits of CBD.
Even though some users experience arrhythmia-like symptoms from CBD, an animal study from 2010 found that an acute administration of CBD suppressed ischaemia-induced arrhythmia.
Ischaemia is a restriction of blood to tissues, which causes a shortage of oxygen that is necessary for keeping tissues alive.
The researchers also stated that CBD reduced the size of infarction (tissue death), when it was given at reperfusion injury.
A 2013 review mentioned that current evidence suggests CBD has positive effects on the cardiovascular system, but that clinical research on human participants is required to determine if these positive effects will translate to the human cardiovascular system.
Finally, a 2018 review stated that cannabinoids appear as promising therapeutic agents for cardiovascular diseases.
Since the research on the effects of CBD on arrhythmia (and the cardiovascular system in general) is still in its starting phases, it probably isn’t wise to consume it for these purposes until more is known on the subject.
On the other hand, if you’re experiencing heart palpitations from CBD products, make sure to follow our guidelines regarding different types of CBD products.
If these heart-related symptoms persist, you can also consider lowering the dose or perhaps even discontinuing your CBD regimen.
Get the essential information related to CBD and heart arrhythmia. Modern studies and anecdotal reports are included.